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Use with caution in extreme hepatic impairment, aged, and individuals having a record of depression or psychosis (modafinil may possibly exacerbate psychiatric indications) or maniaAltered depolarization specifications of neurons via variations in sodium homeostasis, or enhanced calcium inflow could describe greater neurotransmitter launch (which c
Coming off extensive-phrase lorazepam use can be more realistically reached by a gradual swap to an equivalent dose of diazepam as well as a duration of stabilization on this, and only then initiating dose reductions.Drug and Liquor dependence – The chance of abuse of lorazepam is elevated in dependent people.[seventy six]The chance of dependence
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